Ratiani L, Gabunia L, Machavariani K, Khetsuriani Sh, Gamkrelidze N, Varazi E, Shoshiashvili V
The outbreak COVID-19 which had begun from China at the end of 2019 is a major public health issue. Public health and infection control measures are urgently required to limit the spread of this global viral infection. 160 COVID-19patients were admitted to the First University Clinic of Tbilisi State Medical University (TSMU) during March-June 2020. We provided the retrospectivestudy of these cases according to gender and age of patients, lethal outcome rate, hospitalization days and frequency of different comorbid diseases. Also, observations were carried out on patients taking angiotensin converting enzyme(ACE) inhibitors and angiotensin-AT1 receptor blockers due to heart failure or arterial hypertension. Among COVID-19 patients, frequency of lethal outcome was not significantly different between female and male genders (44.4% vs. 55.6%). Prevalence of this disease was the most common in patients with 30-59 years of ages (45.3%). Average hospitalization days were 21. Mortality rate was 5.6%, mostly in age above 60 (88.8%). Among lethal outcome patients, 88.8% had comorbid diseases. Heart failure, acute kidney injury, sepsis, essential arterial hypertension III, mitral valve defect, nontoxic diffuse goiter and etc; were the most common underlying conditions. Recovering of COVID- patients 19with arterial hypertension(55%) who were not treated with angiotensin-converting enzyme inhibitors and angiotensin-AT1 receptor blockers required fewer hospitalization days to recover (approximately 2-3 days or 62 hours less) in comparing to patients which were treated using the above mentioned medications.