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Artigo de Pesquisa

Validation of Next Generation Sequencing Cancer Panels for Clinical Somatic Mutation Profiling-- Identification of Source of Variations and Artifacts using FFPE Tissues

Ken CN Chang*, Yun Zhao, John Kang, Saumya Pant, Ping Qiu, Bo Wei, Russell Weiner and Matthew J Marton

Use of a Next Generation Sequencing (NGS)-based test as a clinical trial assay requires that the test be analytically validated to CLIA/CAP regulations. During the course of ana..Veja mais»

Artigo de Pesquisa

KDR Mutation: A High-Frequency Rare Mutation and its Correlation with other Somatic Mutations in Indian Colorectal Cancer Patients

Mayank Jauhri, Vani Gupta, Yogender Shokeen, Sachin Minhas, Sunita Bhalla and Shyam Aggarwal

Aim: This study aims to find out the frequency of KDR mutation in colorectal cancer patients and if any correlation exists between KDR mutation and demographica..Veja mais»

Mini Review

Reactive Oxygen Species and Nuclear Factor Erythroid 2-Related Factor 2 Activation in Diabetic Nephropathy: A Hidden Target

Shaaban Abdo, Shao-Ling Zhang and John S.D. Chan

Hyperglycemia, oxidative stress and renin-angiotensin system (RAS) dysfunction have been implicated in diabetic nephropathy (DN) progression, but the underlying..Veja mais»

Artigo de Pesquisa

Serum Vitamin D Level in Children with and without Type 1 Diabetes Mellitus

Halioui-Louhaichi Sonia, Mrabet Ali, Dridi Yousr, Barbaria Wiem, Hamzaoui Anies Hamzaoui Kamel and Maherzi Ahmed

For years, vitamin D has been associated to many immune disorders. Several studies have shown association between low serum 25 OH vitamin D and type 1 diabetes ..Veja mais»

Artigo de Pesquisa

Assessment of Cholesterol Absorption and Synthesis in Japanese Patients with Type-2 Diabetes and Lipid-Lowering Effect of Ezetimibe

Tomoko Nakagami, Yayoi Yamamoto, Sayaka Fukushima, Junko Oya, Yasuhiko Iwamoto and Yasuko Uchigata

Aims: Cholesterol absorption is reported as an independent risk factor for cardiovascular disease. However, factors related to cholesterol absorption have not been fully examine..Veja mais»

Pesquisar

Augmentative Modeling: A Pattern for Populus spp. Stand Biomass in the Eurasia under the Influence of Climate Change

Vladimir Andreevich Usoltsev, Seyed Omid Reza Shobairi, Ivan Stepanovich Tsepordey, Viktor Petrovich Chasovskikh

Based on the generated database of 413 sample plots with definitions of stand biomass of the genus Populus spp. in Eurasia, from France to Japan and southern China, statisticall..Veja mais»