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Perspectiva

Brain Metastases from Breast Cancer Treated with Neurosurgery

Paulo Roriz

Breast cancer is the most prevalent cancer in women globally, and metastasis is the leading factor in breast cancer patients’ deaths. 10% to 16% of patients with metastati..Veja mais»

Comunicação curta

Dose-Effect of a 6-week treatment with PEP2DIA® on sucrose tolerance in Goto-Kakizaki (GK) rats

Audrey Boulier

Diabetes means the blood glucose, or blood sugar, levels are too high. With type 2 diabetes, the more common type, your body does not make or use insulin well. Insulin is a horm..Veja mais»

Artigo de Pesquisa

Treatment of Morbid Obesity

Shahid Habib, Julia Samamé, Carlos A Galvani

Prevalence of obesity is increasing and approaching a pandemic. It is largely driven by changes in living environment and behavior as a result of technological modernization. Th..Veja mais»

Pesquisar

Effect of Hydroxychloroquine on Type 2 Diabetes Mellitus Unresponsive to More Than Two Oral Antidiabetic Agents

Jagnani VK, Bhattacharya NR, Satpathy SC, Hasda GC and Sourav Chakraborty

Background and aims: The aims of the present study were to evaluate the effectiveness of Hydroxychloroquine as an add-on therapy to metformin and Sulfonylurea (SU) in reducing g..Veja mais»

Artigo de Pesquisa

A Polymorphic Microdeletion in the RGS9 Gene Suppresses PTB Binding and Associates with Obesity

Chong Shen, Meenakshi Sharma, Daniel C Reid, Pengtao Li, Jeremy Celver, Norhashimah Abu Seman, Jinfeng Chen, Senthil K Vasan, Hairu Wang, Tianwei Gu, Ying Liu, Wan Nazaimoon Wan Mohamud, Hongbing Shen, Kerstin Brismar, William G Fairbrother, Abraham Kovoor and Harvest F Gu

Objective: RGS9 is a member of the family of Regulators of G-Protein Signaling (RGS) proteins defined by the presence of an RGS domain which can accelerate the ..Veja mais»

Artigo de Pesquisa

Higher Plasma Concentrations of the Methylglyoxal Metabolite D-lactate are Independently Associated with Insulin Resistance: The CODAM Study

Dionne EM Maessen, Jean LJM Scheijen, Katrien H Gaens, Marleen MJ van Greevenbroek, Carla J van der Kallen, Coen DA Stehouwer and Casper G Schalkwijk

Objective: Methylglyoxal (MGO), a highly reactive dicarbonyl compound generated by the spontaneous degradation of glycolytic intermediates, is a major precursor for advanced gly..Veja mais»