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Artigo de Pesquisa

HLA-DR, HLA-DQ Haplotypes and Diabetic Autoantibodies in Nondiabetic Siblings of Type I Diabetes

Sitelbanat Awadalla and Manan AL Hakbany

The screening of non-diabetic siblings of Saudi type 1 diabetes mellitus (T1DM) patients (n=54) and 50 healthy controls was undertaken for glutamic acid decarboxylase (anti-GAD)..Veja mais»

Relato de caso

Scar Site Bullous Pemphigoid: A Rare Presentation and a Clinician Dilemma

Shadab Doi

Bullous pemphigoid is the most common autoimmune subepidermal blistering disease. Its onset is usually after 60 years of age. Characteristically, BP is an intensely prurit..Veja mais»

Artigo de revisão

Androgen Receptor Signaling in Prostate Cancer: New Twists for an Old Pathway

Junjie Feng, S Lilly Zheng, Wennuan Liu, William B. Isaacs and Jianfeng Xu

 Secretory leukocyte protease inhibitor is a multifunctional protein with a variety of activities attributed to it. A significant increase in the expression of Secretory le..Veja mais»

Artigo de Pesquisa

Effects of Metformin Treatment on Myocardial and Endothelial Function in Insulin Resistance Patients: A Metabolomic Study

Martino Deidda, Silvio Nocco, Emanuela Locci, Efisio Cossu, Marco G Baroni, Luigi Atzori and Giuseppe Mercuro

Introduction: Insulin resistance (IR) adversely affects cardiac performance and peripheral vasodilation reserve. Metformin, prescribed to prevent the progressio..Veja mais»

Resumo estendido

The international debate on the Mechanisms of the progression from Barrett’s esophagus to esophageal adenocarcinoma: role of NADPH oxidase NOX5-S

Weibiao Cao

Esophageal adenocarcinoma (EA) has increased in incidence over the past several decades and is characterized by a poor prognosis. Gastroesophageal reflux disease (GERD) complica..Veja mais»

Artigo de revisão

Antiplatelet Therapy, Diabetic Neuropathy and Peripheral Vascular Disease: A Unitary Approach

Takahisa Deguchi, Raymond L. Rosales, Teruto Hashiguchi and Kimiyoshi Arimura

Although pathologically not necessarily the same, germane to both diabetic neuropathy and peripheral vascular disease is the morbid vascular complication of diabetes mellitus. A..Veja mais»