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Artigo de Pesquisa

Higher Plasma Concentrations of the Methylglyoxal Metabolite D-lactate are Independently Associated with Insulin Resistance: The CODAM Study

Dionne EM Maessen, Jean LJM Scheijen, Katrien H Gaens, Marleen MJ van Greevenbroek, Carla J van der Kallen, Coen DA Stehouwer and Casper G Schalkwijk

Objective: Methylglyoxal (MGO), a highly reactive dicarbonyl compound generated by the spontaneous degradation of glycolytic intermediates, is a major precursor for advanced gly..Veja mais»

Relato de caso

Correction of Overlapping Fifth Toe Deformity with Combination of Z-Plasty and Transposition Skin Flap

Tekin Simsek, Engin Yosma, Asef Abdullayev, Bulent Demir and Ibrahim Alper Aksakal

Overlapping fifth toe is a congenital deformity and is characterized by an external rotation of the toe so that it overrides the adjacent fourth toe. Treatment of this condition..Veja mais»

Artigo de Pesquisa

Orally-Administered Chemokine Receptor CCR2 Antagonist CCX140-B in Type 2 Diabetes: A Pilot Double-Blind, Randomized Clinical Trial

Markolf Hanefeld, Ernest Schell, Ioanna Gouni-Berthold, Martin Melichar, Ivana Vesela, Dan Johnson, Shichang Miao, Tim J Sullivan, Juan C Jaen, Thomas J Schall, Pirow Bekker and The CCX140-B Diabetes Study Group

Study background: Inflammatory macrophages expressing the C-C chemokine receptor 2 (CCR2) accumulate in adipose tissue and contribute to insulin resistance. CCX140-B is an orall..Veja mais»

Comunicação curta

During the Nestling Period, Testosterone and Heterospecific Aggression were Observed In Adult Eastern Bluebirds (Sialia sialis)

Jennifer Stewart

Conspecific competition is thought to have a stronger selection effect on aggressive behaviour and its underlying physiology in birds than the heterospecific competition. ..Veja mais»

Artigo de Pesquisa

Association of Protein Tyrosine Phosphatase Non-receptor, Type 22 (PTPN22) C1858T Polymorphism with Type 1 Diabetes in North India: A Replication Study

Rajni Rani, Neetu Israni, Avinash Kumar, Smreti Vasudevan and Jaya Singh

Objective: Type 1 diabetes (T1D) is a multifactorial autoimmune disorder where several genes have been associated with the disease. While the major histocompati..Veja mais»

Artigo de Pesquisa

Performance Evaluation of WRF-CHEM in Simulating Harmattan Dust over West Africa

Elijah Adesanya Adefisan and Amarachi Jovita Oghaego

In this study, we investigated the ability of Weather Research and Forecasting model coupled with the Chemistry option (WRF-Chem) using the GOCART dust scheme in capturing the s..Veja mais»