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Artigo de Pesquisa

Orally-Administered Chemokine Receptor CCR2 Antagonist CCX140-B in Type 2 Diabetes: A Pilot Double-Blind, Randomized Clinical Trial

Markolf Hanefeld, Ernest Schell, Ioanna Gouni-Berthold, Martin Melichar, Ivana Vesela, Dan Johnson, Shichang Miao, Tim J Sullivan, Juan C Jaen, Thomas J Schall, Pirow Bekker and The CCX140-B Diabetes Study Group

Study background: Inflammatory macrophages expressing the C-C chemokine receptor 2 (CCR2) accumulate in adipose tissue and contribute to insulin resistance. CCX140-B is an orall..Veja mais»

Artigo de revisão

Inhibition of 12/15-Lipoxygenase Reduces Renal Inflammation and Injury in Streptozotocin-Induced Diabetic Mice

Jessica Faulkner, Chelsey Pye, Mohamed Al-Shabrawey and Ahmed A Elmarakby

Previous studies suggest that 12/15 lipoxygenase (12/15-LO) is implicated in diabetic vascular complications. We hypothesize that 12/15-LO inhibition attenuates renal inflammati..Veja mais»

Artigo de Pesquisa

Epidemiology of Impaired Renal Function in the Bamenda Health District, North West Region of Cameroon

Tetuh KM, Thomas VA, Fomboh R, Yongsi BN, Mankolo BO and Alberic S

Impaired renal function (IRF) is a worldwide problem with adverse outcome of kidney failure, cardiovascular disease (CVD) and death. Consequently research on assessing the burde..Veja mais»

Artigo de revisão

Geophysical Monitoring and Evaluation Criteria of Climate Change

Singh P, Singh RD, Rajput P

The global climate change indicates increasing geophysical incidences, earthquakes, cyclones, melting of glaciers, floods, and drought etc. These incidences are the impacts of g..Veja mais»

Artigo de Pesquisa

Is There A Relationship Between Visfatin Level and Type 2 Diabetes Mellitus In Obese And Non Obese Patients?

Eid M El-Shafey, Gamal F El-Naggar, Mohamed M Al-Bedewy and Hesham El-Sorogy

Background: Visfatin is a newly discovered cytokine that is highly expressed in visceral fat with a direct relationship to type 2 diabetes mellitus (T2DM). The present study was..Veja mais»

Artigo de Pesquisa

Comparison of Glycemic Control Indicators and Safety Evaluation during Linagliptin Treatment over 6 Months in Japanese Type 2 Diabetic Patients with and without Nephropathy

Masami Tanaka, Takeshi Nishimura, Risa Sekioka, Toshihide Kawai, Shu Meguro, Junichiro Irie, Yoshifumi Saisho and Hiroshi Itoh

Objective: This retrospective study was undertaken to compare hemoglobin A1c and glycoalbumin levels as glycemic control indicators during linagliptin treatment..Veja mais»