Onkar Dighe, Priti Ghanshyam Verma, Surekha Tayade
Bilateral Renal Agenesis is not compatible in extrauterine life. Pulmonary hypoplasia develops in the absence of amniotic fluid, causing severe respiratory insufficiency at birth. Renal agenesis can result from the complete regression of a dysplastic kidney. It might be a unilateral or bilateral problem. A preexisting diabetic condition is linked to bilateral renal agenesis. The majority of instances of bilateral agenesis are sporadic. However, genetic variables have a role in pathogenesis, and multifactorial inheritance is a plausible explanation, exact manner of genetic inheritance is unclear. There have also been reports of X-linked, autosomal recessive, and autosomal dominant inheritance. Bilateral/unilateral renal agenesis, renal hypodysplasia (a reduction in the number of nephrons resulting to a small overall kidney size and frequent dysplasia with or without cysts), and multicystic dysplastic kidneys are all examples of developmental renal abnormalities (MCDK).A kidney can be missing because it never developed (agenesis [possibly rare]) or because a dysplastic kidney has completely regressed (aplasia/MCDK). The term "renal agenesis" will be used in the following topic review to refer to missing kidneys caused by either of these etiologies. The youngster who lived the longest lived for 39 days among various cases. However, in bilateral renal dysplasia treated with continuous intrauterine amnioinfusion, a 9-month survival rate was seen in generally. Diagnosis of this condition is made by various investigations like NT scan with double markers, Ultrasonography, per abdominal examination. Awareness about the patient’s condition and counselling of relatives was done. Termination of pregnancy was done in this case.