Riya Gulalkari, Kirti Chaudhari
Background: The CAKUT-congenital abnormalities of kidneys and urinary tract are various groups of conditions which, jointly are among those foremost abnormalities that are found in newly born children. CAKUTs are produced via way of means of mutations in an exceptionally massive quantity of genes that showcase a huge variety of symptoms, which is consistent with their variety. The vast bulk of duplex irregularities is asymptomatic and has no therapeutic potential. However, such kidneys having double ureter can cause problems. Methodology: Early identification of these malformations in the patients is crucial since serious problems are noticeable and can be adequately dealt with early management. A duplex aggregation system is that the most typical malformation of the tract and reflux is the most common abnormality related to it. Result: The vast majority of asymptomatic kidney duplications are discovered by chance and appear to be misdiagnosed as kidney which is normally functioning with whole or incomplete duplication. Though the association between urinary tract infection, vesicoureteral reflux, and parenchymal scarring during a non-duplicated collecting system is standard, very little has been written regarding the prevalence and distribution of vesicoureteral reflux and parenchymal scarring in duplicated systems. Induction of the ureter, reviews genes which are considered not only as hazardous factors in the development of renal duplexes but also discusses the molecular and cellular mechanisms that might give rise to such kind of mutation. Conclusion: In this review, we will be concentrating on double ureter kidneys, which is a common type of CAKUT which is symptomless still makes prone to hydronephrosis and vesicoureteric reflux.