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Epigenetic Modifications Influence Gene Expression and Contr | 129686

Jornal de Diabetes e Metabolismo

ISSN - 2155-6156

Abstrato

Epigenetic Modifications Influence Gene Expression and Contribute to the Development of Obesity, Diabetes, and Related Metabolic Disorders

Tobias Steiner

Epigenetics, a field delving into heritable changes in gene expression without altering DNA sequences, is pivotal in deciphering the roots of metabolic disorders. This report illuminates the nuanced connection between epigenetic intricacies and metabolic irregularities in a patient grappling with obesity, insulin resistance, and dyslipidemia. Employing a multifaceted approach encompassing epigenetic profiling, genetic scrutiny, and metabolic evaluations, substantial epigenetic alterations were unearthed in genes pivotal to metabolic pathways. This case serves as a poignant reminder of the indispensable role of epigenetic considerations in both diagnosing and managing metabolic disorders. By scrutinizing epigenetic landscapes alongside traditional genetic and metabolic assessments, clinicians gain a holistic understanding of disease etiology, facilitating tailored therapeutic strategies. Epigenetic modifications, responsive to environmental cues, delineate an intricate web influencing gene expression and metabolic homeostasis. Embracing this paradigm shift in clinical practice not only enhances diagnostic precision but also unveils promising avenues for personalized interventions targeting epigenetic mechanisms. In essence, this case underscores the imperative of integrating epigenetic insights into the fabric of metabolic disorder management, heralding a new era of precision medicine.

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